Page 353 - ALERGIAS BÁSICAS
P. 353

●  Incremento  documentado  en  el  marcador  sobre  el  valor  basal  durante  un  periodo
                       sintomático en al menos dos ocasiones (en caso de niveles persistentes de triptasa
                       >15 ng, basta con un aumento sobre el valor basal en una ocasión).
                   ●  La  triptasa  sérica  total  es  el  marcador  de  elección,  siendo  menos  específica  la
                       medición  en  orina  de  24  horas  de  los  metabolitos  de  histamina  así  como  la
                       prostaglandina D2 o su metabolito 11-β prostaglandina F2 (también procedentes del
                       basófilo).





               BIBLIOGRAFÍA RECOMENDADA

               SANCHEZ-BORGES  M,  ET  AL.Diagnosis  and  Treatment  of  Urticaria  and  Angioedema:  A
               Worldwide Perspective. WAO Journal 2012; 5:125–147.

               T. ZUBERBIER, R. ASERO, C. BINDSLEV-JENSEN, ET AL. EAACI/GA2LEN/EDF/WAO guideline:
               definition, classification and diagnosis of urticaria. Allergy 2009: 64: 1417–1426

               MAGERL, M., ET AL., The definition and diagnostic testing of physical and cholinergic urticarias–
               EAACI/GA2LEN/EDF/UNEV  consensus  panel  recommendations.  Allergy,  2009.  64(12):  p.
               1715-21.

               KAPLAN AP. EN: ADKINSON, N.F. AND E. Middleton, Middleton’s allergy: principles & practice.
               7th ed. 2009, Philadelphia, PA: Mosby/Elsevier.

               SOTLAR K, ESCRIBANO L, LANDT O, ET AL. One-Step Detection of c-kit Point Mutations Using
               PNA-Mediated PCR-Clamping and Hybridization Probes. Am.J.Pathol 2002;81:677-90.


               GONZÁLEZ DE OLANO D, DE LA HOZ CABALLER B, NÚÑEZ LÓPEZ R, ET AL. Prevalence of allergy
               and anaphylactic symptoms in 210 adult and pediatric patients with mastocytosis in Spain: a
               study  of  the  Spanish  network  on  mastocytosis  (REMA).  Clin  Exp  Allergy.  2007
               Oct;37(10):1547-55.

               VALENT  P,  HORNY  H-P,  ESCRIBANO  L,  ET  AL.Diagnostic  Criteria  and  Classification  of
               Mastocytosis: A Consensus Proposal. Leuk.Res. 2001;25:603-25.

               DE LA HOZ B, GONZÁLEZ DE OLANO D, ALVAREZ I, ET AL. [Guidelines for the diagnosis, treatment
               and management of mastocytosis]. An Sist Sanit Navar. 2008; 31(1):11-32.


               VALENT P, HORNY H-P, LI CY, ET AL. Mastocytosis (Mast cell disease). In Jaffe ES, Harris NL,
               Stein H, Vardiman JW, eds.  World Health Organization (WHO) Classification of Tumours.
               Pathology & Genetics. Tumours of Haematopoietic and Lymphoid Tissues., pp 291-302. 2001.


               VALENT P, AKIN C, AROCK M, BROCKOW K,ET AL. Definitions, criteria and global classification of
               mast cell disorders with special reference to mast cell activation syndromes: a consensus
               proposal. Int Arch Allergy Immunol. 2012; 157(3): 215-25.









                                                                                                      349
   348   349   350   351   352   353   354   355   356   357   358